Opsin-like immunoreaction in the retinae and pineal organs of four mammalian species

Research output: Contribution to journalArticle


Opsin-like immunoreactivity was observed in the retinae and pineal organs of the mouse, rat and guinea pig, and the pineal organ of the cat. In the retina the immunoreaction was restricted to photoreceptor cells, which displayed immunostaining in their perikarya and outer and inner segments. Distinct pinealocytes endowed with characteristic processes were labelled in the pineal organs of the mouse and cat. However, in the cat the number of immunoreactive pinealocytes was very limited. In the pineal organs of the rat and guinea pig immunoreaction was very weak and diffuse. No immunoreaction was observed when the antibody was preabsorbed with purified bovine (rhod)opsin. These findings are in accord with the results of previous studies indicating molecular similarities between retinal photoreceptors and pinealocytes in mammals.


External organisations
  • Justus Liebig University Giessen
  • Radboud University Nijmegen
  • University of Oxford
  • Lund University
Research areas and keywords


  • Mammals, Opsin-like immunoreactivity, Photopigments, Photoreceptors, Pineal organ, Pinealocytes, Retina
Original languageEnglish
Pages (from-to)645-648
Number of pages4
JournalCell and Tissue Research
Issue number3
Publication statusPublished - 1985 Dec 1
Publication categoryResearch
Externally publishedYes