Orthotopic Wilms tumor xenografts derived from cell lines reflect limited aspects of tumor morphology and clinical characteristics.

Research output: Contribution to journalArticle

Abstract

Wilms tumor (WT) is a pediatric tumor of the kidney, the treatment of which includes heavy chemotherapy. Affected children would likely benefit from more targeted therapies with limited side effects. Establishment of relevant orthotopic WT xenografts is important to better understand mechanisms of WT growth and for preclinical drug testing.

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Subject classification (UKÄ) – MANDATORY

  • Pediatrics
Original languageEnglish
Pages (from-to)1949-1954
JournalPediatric Blood & Cancer
Volume61
Issue number11
Publication statusPublished - 2014
Publication categoryResearch
Peer-reviewedYes

Related research output

Sehic, D., 2014, Division of Clinical Genetics, Lund University. 104 p.

Research output: ThesisDoctoral Thesis (compilation)

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