Oxaspirodion, a new inhibitor of inducible TNF-alpha expression from the ascomycete Chaetomium subspirale

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Abstract

In a search for new inhibitors of the TNF-alpha promoter activity, a new spiro-compound, designated oxaspirodion, was obtained as a mixture of four isomers from fermentations of the ascomycete Chaetomium subspirale. The structure was determined by a combination of spectroscopic techniques.

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Subject classification (UKÄ) – MANDATORY

  • Organic Chemistry
Original languageEnglish
Pages (from-to)493-495
JournalJournal of Antibiotics
Volume57
Issue number8
Publication statusPublished - 2004
Publication categoryResearch
Peer-reviewedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240)