Pediatric contact allergy: A comparative study with adults

Research output: Contribution to journalArticle


Background: Pediatric allergic contact dermatitis is increasing. The patch-test allergens included in pediatric baseline series vary globally. The worldwide prevalence of pediatric reactions to allergens needs clarification. Objectives: Identify the prevalence, associated factors, and culprit allergens for contact allergy among patch-tested Thai children, and compare with those for adults. Methods: Baseline-series patch-test results from 2010–2019 were collected for patients younger than 18 years of age. As a control group, sex-matched adult patients were randomly selected. The results and characteristics of the two groups were compared. Results: The median age of 112 patch-tested pediatric patients was 16 (range 2–17) years. Of the children, 35.5% had at least one positive reaction, significantly less than the 56.6% for adults. The five most common pediatric allergens were nickel sulfate (12.1%), potassium dichromate (8.0%), methylisothiazolinone (7.1%), fragrance mix II (6.0%), and carba mix (5.4%). Although similar, the 10 most common allergens of the groups differed in order. Positive reactions to cosmetic allergens were significantly less frequent among the children. Many allergens remained entirely negative. Conclusions: The prevalence of positive reactions was lower in children, varying by population and region. The top-10 pediatric and adult causative allergens were almost identical. We recommend using the same baseline patch-test series for children and adults in our region.


External organisations
  • Mahidol University
  • Siriraj Hospital
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Dermatology and Venereal Diseases


  • allergic contact dermatitis, atopic dermatitis, prevalence, children, epidemiology, patch test, pediatric
Original languageEnglish
Pages (from-to)34-40
Number of pages7
JournalContact Dermatitis
Issue number1
Early online date2020 Jul 22
Publication statusPublished - 2021 Jan
Publication categoryResearch