Persistence and evolution of allergen-specific IgE repertoires during subcutaneous specific immunotherapy.

Research output: Contribution to journalArticle

Abstract

Specific immunotherapy (SIT) is the only treatment with proved long-term curative potential in patients with allergic disease. Allergen-specific IgE is the causative agent of allergic disease, and antibodies contribute to SIT, but the effects of SIT on aeroallergen-specific B-cell repertoires are not well understood.

Details

Authors
  • Mattias Levin
  • Jasmine J King
  • Jacob Glanville
  • Katherine J L Jackson
  • Timothy J Looney
  • Ramona A Hoh
  • Adriano Mari
  • Morgan Andersson
  • Lennart Greiff
  • Andrew Z Fire
  • Scott D Boyd
  • Mats Ohlin
Organisations
External organisations
  • Stanford University
  • Istituto Dermopatico dell'Immacolata
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Respiratory Medicine and Allergy
Original languageEnglish
Pages (from-to)1535-1544
JournalThe Journal of Allergy and Clinical Immunology
Volume137
Issue number5
Early online date2015 Nov 7
Publication statusPublished - 2016
Publication categoryResearch
Peer-reviewedYes