Personalised, predictive and preventive medicine: a decision-theoretic perspective

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Personalised, predictive and preventive medicine: a decision-theoretic perspective. / Sahlin, Nils-Eric; Hermerén, Göran.

In: Journal of Risk Research, Vol. 15, No. 5, 2012, p. 453-457.

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TY - JOUR

T1 - Personalised, predictive and preventive medicine: a decision-theoretic perspective

AU - Sahlin, Nils-Eric

AU - Hermerén, Göran

PY - 2012

Y1 - 2012

N2 - Background. The last decade has witnessed remarkable developments in medical treatment that is personalised, predictive and preventive. The advances made here have the potential to bring about radical change, not only in diagnostic tests and prescriptions, but also in more fundamental patterns in the provision of health care. Methods. The conceptual framework and principles of modern decision theory are applied to some of the ethical issues raised by recent advances in personalised, predictive and preventive medicine, including questions about limits of autonomy and the implications of justice and fairness in the distribution of health care services. Results. A new way of conceptualising and understanding the ethical issues raised by personalised, predictive and preventive medicine is sketched. Such medicine involves decisions under risk and decisions under uncertainty, depending on the extent to which current knowledge gaps can be filled. Conclusions. The various ways of conceptualising and understanding these problems need to be discussed before personalised, predictive and preventive medicine is implemented in practical health care.

AB - Background. The last decade has witnessed remarkable developments in medical treatment that is personalised, predictive and preventive. The advances made here have the potential to bring about radical change, not only in diagnostic tests and prescriptions, but also in more fundamental patterns in the provision of health care. Methods. The conceptual framework and principles of modern decision theory are applied to some of the ethical issues raised by recent advances in personalised, predictive and preventive medicine, including questions about limits of autonomy and the implications of justice and fairness in the distribution of health care services. Results. A new way of conceptualising and understanding the ethical issues raised by personalised, predictive and preventive medicine is sketched. Such medicine involves decisions under risk and decisions under uncertainty, depending on the extent to which current knowledge gaps can be filled. Conclusions. The various ways of conceptualising and understanding these problems need to be discussed before personalised, predictive and preventive medicine is implemented in practical health care.

KW - personalised medicine

KW - risk taking

KW - decision-making

U2 - 10.1080/13669877.2011.634524

DO - 10.1080/13669877.2011.634524

M3 - Article

VL - 15

SP - 453

EP - 457

JO - Journal of Risk Research

JF - Journal of Risk Research

SN - 1366-9877

IS - 5

ER -