Photocoagulation of human retinal pigment epithelial cells in vitro: evaluation of necrosis, apoptosis, cell migration, cell proliferation and expression of tissue repairing and cytoprotective genes.

Research output: Contribution to journalArticle


Sight-threatening diabetic retinopathy has been treated with photocoagulation for decades but the mechanisms behind the beneficial clinical effects are poorly understood. One target of irradiation and a potential player in this process is the retinal pigment epithelium (RPE). Here we establish an in vitro model for photocoagulation of human RPE cells.


Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Ophthalmology
  • Endocrinology and Diabetes
Original languageEnglish
Article numbere70465
JournalPLoS ONE
Issue number8
Publication statusPublished - 2013
Publication categoryResearch

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Unit on Vascular Diabetic Complications (013241510), Ophthalmology (013242810), Department of Clinical Sciences, Malmö (013240000)

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