Photocoagulation of human retinal pigment epithelium in vitro: unravelling the effects on ARPE-19 by transcriptomics and proteomics.

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Abstract

Despite the extensive use of retinal photocoagulation for ischaemia and vascular leakage in retinal vascular disease, the molecular mechanisms behind its clinical beneficial effects are still poorly understood. One important target of laser irradiation is the retinal pigment epithelium (RPE). In this study, we aimed at identifying the isolated effects of photocoagulation of RPE at both the mRNA and protein expression levels.

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  • Ophthalmology
Original languageEnglish
Pages (from-to)348-354
JournalActa Ophthalmologica
Volume93
Issue number4
Publication statusPublished - 2015
Publication categoryResearch
Peer-reviewedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Ophthalmology (013242810), Unit on Vascular Diabetic Complications (013241510), Diabetes and Celiac Unit (013241540), Department of Clinical Sciences, Malmö (013240000)