Plasma homocysteine in 80-year-olds Relationships to medical, psychological and social variables.

Research output: Contribution to journalArticle


Plasma homocysteine concentrations in a group of 80-year-old persons were related to symptoms and signs. Plasma homocysteine concentrations higher than 15 mumol/l were associated with lower total life satisfaction (P<0.01), mood (P<0.05), zest for life (P<0.05), lower scores for reasoning (P<0.05), spatial ability (P<0.05), memory recognition (P<0.05), and subjective health (P<0.01). In an instrument comprising of 30 symptoms, plasma homocysteine concentrations higher than 15 mumol/l were associated with impaired concentration (P<0.05), restlessness (P<0.05), feeling cold (P<0.05), loss of weight (P<0.05), and feeling depressed (P<0.01). The above data indicate that plasma homocysteine values over 15 mumol/l could be relevant markers for clinical intervention.


  • E Jensen
  • Ove Dehlin
  • Eva Marie Erfurth
  • Bo Hagberg
  • Gillis Samuelsson
  • Torbjörn Svensson
  • Björn Hultberg
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Gerontology, specializing in Medical and Health Sciences
Original languageEnglish
Pages (from-to)215-226
JournalArchives of Gerontology and Geriatrics
Issue number3
Publication statusPublished - 1998
Publication categoryResearch

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Division of Clinical Chemistry and Pharmacology (013250300), Division of Geriatric Medicine (013040040), Division of Occupational Therapy (Closed 2012) (013025000), Medicine (Lund) (013230025), Department of Psychology (012010000)