Plasma level of the endogenous sodium pump ligand marinobufagenin is related to the salt-sensitivity in men.

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Abstract

Salt-induced elevation of the endogenous digitalis like sodium pump ligand marinobufagenin (MBG) in the Dahl salt-sensitive rats resulted in elevated blood pressure (BP). Here, we tested, in humans, whether MBG levels are related to ambulatory 24-h BP (ABP), controlled long-term increase of salt-intake induces changes in MBG and any salt-induced change in MBG is related to salt sensitivity.

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Subject classification (UKÄ) – MANDATORY

  • Cardiac and Cardiovascular Systems
Original languageEnglish
Pages (from-to)534-541
JournalJournal of Hypertension
Volume33
Issue number3
Publication statusPublished - 2015
Publication categoryResearch
Peer-reviewedYes