Platelet-derived S100A8/A9 and cardiovascular disease in systemic lupus erythematosus.
Research output: Contribution to journal › Article
S100A8/A9, a pro-inflammatory and pro-thrombotic protein complex, is increased in several diseases and high levels predispose to cardiovascular disease (CVD). Recently, platelet S100A8/A9 synthesis was described in mouse and humans in relation to CVD. However, the role of platelet S100A8/A9 in systemic lupus erythematosus (SLE), a disease with markedly increased cardiovascular morbidity, as well as the exact platelet distribution of the S100A8/A9 proteins has not been investigated.
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Journal||Arthritis & Rheumatology|
|Early online date||2016 Mar 4|
|Publication status||Published - 2016|