Population Pharmacokinetics of Plasma-Derived Factor IX: Procedures for Dose Individualization.

Research output: Contribution to journalArticle

Abstract

Population pharmacokinetic (POPPK) models describing factor IX activity levels in plasma, in combination with individual factor IX measurements, may be used to individualize dosing in the treatment of hemophilia B.

Details

Authors
  • Ari Brekkan
  • Erik Berntorp
  • Kirsten Jensen
  • Elisabet I Nielsen
  • Siv Jönsson
Organisations
External organisations
  • Uppsala University
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Hematology
Original languageEnglish
Pages (from-to)724-732
JournalJournal of Thrombosis and Haemostasis
Volume14
Issue number4
Early online date2016 Jan 25
Publication statusPublished - 2016
Publication categoryResearch
Peer-reviewedYes