Porous silicon immunoaffinity microarrays

Research output: Chapter in Book/Report/Conference proceedingBook chapter

Abstract

Porous silicon with immobilized recognition biomolecules is an attractive platform for many microfluidic chip-based bioanalytical applications. We review the progress in the field since its earliest developments in the 1990s. An improved assay for early detection of prostate cancer has reached clinical evaluation, but there are also exciting developments in both aptamer-based biosensing and mass spectrometry-based biosensing.

Details

Authors
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Medical Laboratory and Measurements Technologies

Keywords

  • Cassie Baxter mode, Desorption/ionization on silicon (DIOS), Fluorescence quenching assay, Immunocapture and MALDI (iMALDI MS), Prostate specific antigen (PSA), Sol-gel aptamer microarrays, Solid/fluid interaction
Original languageEnglish
Title of host publicationHandbook of Porous Silicon
Subtitle of host publicationSecond Edition
EditorsLeigh Canham
PublisherSpringer International Publishing AG
Pages1355-1367
Number of pages13
Volume2-2
Edition2
ISBN (Electronic)9783319713816
ISBN (Print)9783319713793
Publication statusPublished - 2018
Publication categoryResearch
Peer-reviewedYes