Predictive Modeling in Musculoskeletal Mechanobiology

Research output: Chapter in Book/Report/Conference proceedingBook chapter

Abstract

This chapter provides an overview of the main concepts in mechanobiology and touches upon the experimental models that are most frequently used to study mechanobiology on a cell and tissue level. It focuses on the use of computational techniques and algorithms to simulate mechanobiological processes, and their prospective potential in clinical applications. It covers how computational algorithms have developed to include greater and greater biological complexity, and discusses some future challenges in this area. It provides the reader with the main building blocks necessary for performing mechanobiological computer simulations.

Details

Authors
Organisations
External organisations
  • Trinity College Dublin
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Medical Materials

Keywords

  • Computational model, Computer simulation, Differentiation, Fracture healing, Mechanobiology, Mechanoregulation, Musculoskeletal, Regeneration
Original languageEnglish
Title of host publicationMechanobiology: Exploitation for Medical Benefit
PublisherInterscience Wiley
Pages331-346
Number of pages16
ISBN (Electronic)9781118966174
ISBN (Print)9781118966143
Publication statusPublished - 2016 Nov 7
Publication categoryResearch
Peer-reviewedYes