Preparation of diclofenac-imprinted polymer beads for selective molecular separation in water

Research output: Contribution to journalArticle

Abstract

Molecular imprinting technique is an attractive strategy to prepare materials for target recognition and rapid separation. In this work, a new type of diclofenac (DFC)–imprinted polymer beads was synthesized by Pickering emulsion polymerization using 2-(dimethylamino)ethyl methacrylate as the functional monomer. The selectivity and capacity of the molecularly imprinted polymers (MIPs) were investigated in aqueous solution. Equilibrium binding results show that the MIPs have a high selectivity to bind DFC in a wide range of pH values. Moreover, in liquid chromatography experiment, the imprinted polymer beads were packed into column to investigate the binding selectivity under nonequilibrium conditions. The retention time of DFC on the MIP column is significantly longer than its structural analogues. Also, retention of DFC on the MIP column was significantly longer than on the nonimprinted polymer column under aqueous condition. As the new MIP beads can be used to achieve direct separation of DFC from water, the synthetic method and the affinity beads developed in this work opened new possibilities for removing toxic chemicals from environmental and drinking water.

Details

Authors
  • Tongchang Zhou
  • Tripta Kamra
  • Lei Ye
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Polymer Chemistry
  • Biochemistry and Molecular Biology

Keywords

  • aqueous condition, diclofenac, molecular separation, molecularly imprinted polymer beads
Original languageEnglish
Article numbere2608
JournalJournal of Molecular Recognition
Volume31
Issue number3
Publication statusPublished - 2018 Mar 1
Publication categoryResearch
Peer-reviewedYes