Prevalence and Clinical Relevance of Extracardiac Findings in Cardiovascular Magnetic Resonance Imaging

Research output: Contribution to journalArticle

Abstract

Purpose: To assess the prevalence of extracardiac findings (ECF) during cardiovascular magnetic resonance (CMR) examinations and their downstream effect on clinical management. Materials and Methods: We retrospectively identified 500 consecutive patients. Trans-axial balanced steady-state free precession nongated images acquired from the upper thorax to the upper abdomen were evaluated independently by 2 radiologists. ECF were classified as nonsignificant (benign, with no need for further investigation), significant (mandatory to be reported/monitored), and major (clinically remarkable pathology, mandatory to be reported/investigated/treated). Fifteen-month clinical follow-up information was collected through hospital records. Results: Of 500 patients, 108 (21.6%) showed a total of 153 ECF: 59 (11.8% of the entire study population; 38.5% of all ECF) nonsignificant, 76 (15.2%; 49.7%) significant, and 18 (3.6%; 11.8%) major ECF. The most frequent ECF were pleural effusion, hepatic cyst, renal cyst, and ascending aorta dilatation. Of 94 significant and major ECF, 46 were previously unknown and more common in older patients. Newly diagnosed major ECF (n=11, 2.2% of the entire study population, and 7.2% of all ECF)-including 5 tumors (1% of study population)-were confirmed by downstream evaluations and required specific treatment. Patients with major ECF were significantly older than patients without with major ECF. Newly diagnosed clinically significant and major ECF prompted downstream diagnostic tests in 44% and 100% of cases, respectively. Conclusions: The detection of significant and major ECF is common during CMR reporting. The knowledge and the correct identification of most frequent ECF enable earlier diagnoses and faster treatment initiation of unknown extracardiac pathologies in patients referred to CMR imaging.

Details

Authors
  • Cesare Mantini
  • Domenico Mastrodicasa
  • Francesco Bianco
  • Valentina Bucciarelli
  • Michele Scarano
  • Gianluca Mannetta
  • Daniela Gabrielli
  • Sabina Gallina
  • Steffen E. Petersen
  • Fabrizio Ricci
  • Filippo Cademartiri
Organisations
External organisations
  • University of Chieti-Pescara
  • Medical University of South Carolina
  • Lund University
  • Queen Mary University
  • Ospedale Madonna del Soccorso san Benedetto
  • Istituto di Ricerca Diagnostica e Nucleare
  • St Bartholomew's Hospital
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Radiology, Nuclear Medicine and Medical Imaging
  • Cardiac and Cardiovascular Systems

Keywords

  • Cardiac imaging techniques, Incidental findings, Magnetic resonance imaging, Thorax
Original languageEnglish
Pages (from-to)48-55
JournalJournal of Thoracic Imaging
Volume34
Issue number1
Early online date2018 Aug 23
Publication statusPublished - 2019 Jan
Publication categoryResearch
Peer-reviewedYes