Prevalence and Years Lived with Disability of 310 Diseases and Injuries in Iran and its Neighboring Countries, 1990-2015: Findings from Global Burden of Disease Study 2015

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BACKGROUND: Due to significant achievements in reducing mortality and increasing life expectancy, the issue of disability from diseases and injuries, and their related interventions, has become one of the most important concerns of health-related research.

METHODS: Using data obtained from the GBD 2015 study, the present report provides prevalence and years lived with disability (YLDs) of 310 diseases and injuries by sex and age in Iran and neighboring countries over the period 1990-2015. Age-standardized rates of all causes of YLDs are presented for both males and females in 16 countries for 1990 and 2015. We present the percentage of total YLDs for 21 categories of diseases and injuries, the percentage of YLDs for age groups, as well as the ranking of the most prevalent causes and YLDs from the top 50 diseases and injuries in Iran.

RESULTS: In 2015, the burden of 310 diseases and injuries among the Iranian population was responsible for 8,357,878 loss of all-age total years, which is equal to 10.58% of total years lived per year. This differs from the neighboring countries, as it ranges from 9.05% in Turkmenistan to 13.36% in Russia. During the past 25 years, a remarkable decrease was observed in all-cause YLD rates in all 16 countries. Meanwhile, in all countries, the age-standardized rate of all causes of YLDs was higher in females than males.

CONCLUSION: Based on our findings, one of the remarkable changes in NCDs observed among the studied age groups was increased rate of YLDs from mental disorders, which was replaced by musculoskeletal disorders in older age groups in 2015.


  • Shirin Djalalinia
  • Sahar Saeedi Moghaddam
  • Maziar Moradi-Lakeh
  • Saeid Shahraz
  • Mohsen Naghavi
  • Christopher J. L. Murray
  • Theo Vos
  • Ali H Mokhdad
  • Kris Krohn
  • Goodarz Danaei
  • Ashkan Afshin
  • Sadaf G. Sepanlou
  • Shahrzad Bazargan-Hejazi
  • Niloofar Peykari
  • Nazila Rezaei
  • Gholamreza Roshandel
  • Chante Karimkhani
  • Babak Moazen
  • Farshad Pourmalek
  • Ali Reza Esteghamati
  • Nima Hafezi-Nejad
  • Sara Sheikhbahaei
  • Marzieh Katibeh
  • Hamid Ahmadieh
  • Sare Safi
  • Mostafa Qorbani
  • Farhad Islami
  • Ardeshir Khosravi
  • Mohammad Sadegh Hasanvand
  • Mahdi Mahdavi
  • Maryam S Farvid
  • Seyed M Karimi
  • Alireza Mohammadi-Nodooshan
  • Hamid Asayesh
  • Reza Assadi
  • Jagdish Khubchandani
  • Pouria Heydarpour
  • Seyed-Mohammad Fereshtehnejad
  • Saeid Safiri
  • Amir Kasaeian
  • Bagher Larijani
  • Reza Malekzadeh
  • Farshad Farzadfar
External organisations
  • Tehran University of Medical Sciences
  • Iran University of Medical Sciences
  • Tufts Medical Center
  • University of Washington
  • Charles R. Drew University of Medicine and Science
  • Golestan University of Medical Sciences
  • University of British Columbia
  • Shahid Beheshti University of Medical Sciences
  • Alborz University of Medical Sciences
  • American Cancer Society
  • Ministry of Health and Medical Education, Iran
  • Harvard T.H. Chan School of Public Health
  • Baqiyatallah University of Medical Sciences
  • Zamen Salamati co. Ltd.
  • Ball State University
  • Karolinska Institutet
  • Maragheh University of Medical Sciences
  • University of Colorado
  • Heidelberg University
  • University of Qom
  • Harvard University
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Public Health, Global Health, Social Medicine and Epidemiology
Original languageEnglish
Pages (from-to)392-402
Number of pages11
JournalArchives of Iranian Medicine
Issue number7
Publication statusPublished - 2017 Jul
Publication categoryResearch