Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.

Research output: Contribution to journalArticle

Abstract

Cerebral amyloid-β aggregation is an early pathological event in Alzheimer disease (AD), starting decades before dementia onset. Estimates of the prevalence of amyloid pathology in persons without dementia are needed to understand the development of AD and to design prevention studies.

Details

Authors
  • Willemijn J Jansen
  • Rik Ossenkoppele
  • Dirk L Knol
  • Betty M Tijms
  • Philip Scheltens
  • Frans R J Verhey
  • Pieter Jelle Visser
  • Pauline Aalten
  • Dag Aarsland
  • Daniel Alcolea
  • Myriam Alexander
  • Ina S Almdahl
  • Steven E Arnold
  • Inês Baldeiras
  • Henryk Barthel
  • Bart N M van Berckel
  • Kristen Bibeau
  • Kaj Blennow
  • David J Brooks
  • Mark A van Buchem
  • Vincent Camus
  • Enrica Cavedo
  • Kewei Chen
  • Gael Chetelat
  • Ann D Cohen
  • Alexander Drzezga
  • Sebastiaan Engelborghs
  • Anne M Fagan
  • Tormod Fladby
  • Adam S Fleisher
  • Wiesje M van der Flier
  • Lisa Ford
  • Stefan Förster
  • Juan Fortea
  • Nadia Foskett
  • Kristian S Frederiksen
  • Yvonne Freund-Levi
  • Giovanni B Frisoni
  • Lutz Froelich
  • Tomasz Gabryelewicz
  • Kiran Dip Gill
  • Olymbia Gkatzima
  • Estrella Gómez-Tortosa
  • Mark Forrest Gordon
  • Timo Grimmer
  • Harald Hampel
  • Lucrezia Hausner
  • Sabine Hellwig
  • Sanna-Kaisa Herukka
  • Helmut Hildebrandt
  • Lianna Ishihara
  • Adrian Ivanoiu
  • William J Jagust
  • Peter Johannsen
  • Ramesh Kandimalla
  • Elisabeth Kapaki
  • Aleksandra Klimkowicz-Mrowiec
  • William E Klunk
  • Sebastian Köhler
  • Norman Koglin
  • Johannes Kornhuber
  • Milica G Kramberger
  • Koen Van Laere
  • Susan M Landau
  • Dong Young Lee
  • Mony de Leon
  • Viviana Lisetti
  • Alberto Lleó
  • Karine Madsen
  • Wolfgang Maier
  • Jan Marcusson
  • Alexandre de Mendonça
  • Olga Meulenbroek
  • Philipp T Meyer
  • Mark A Mintun
  • Vincent Mok
  • José Luis Molinuevo
  • Hanne M Møllergård
  • John C Morris
  • Barbara Mroczko
  • Stefan Van der Mussele
  • Duk L Na
  • Andrew Newberg
  • Agneta Nordberg
  • Arto Nordlund
  • Gerald P Novak
  • George P Paraskevas
  • Lucilla Parnetti
  • Gayan Perera
  • Oliver Peters
  • Julius Popp
  • Sudesh Prabhakar
  • Gil D Rabinovici
  • Inez H G B Ramakers
  • Lorena Rami
  • Catarina Resende de Oliveira
  • Juha O Rinne
  • Karen M Rodrigue
  • Eloy Rodríguez-Rodríguez
  • Catherine M Roe
  • Uros Rot
  • Christopher C Rowe
  • Eckart Rüther
  • Osama Sabri
  • Páscual Sanchez-Juan
  • Isabel Santana
  • Marie Sarazin
  • Johannes Schröder
  • Christin Schütte
  • Sang W Seo
  • Femke Soetewey
  • Hilkka Soininen
  • Luiza Spiru
  • Hanne Struyfs
  • Charlotte E Teunissen
  • Magda Tsolaki
  • Rik Vandenberghe
  • Marcel M Verbeek
  • Victor L Villemagne
  • Stephanie J B Vos
  • Linda J C van Waalwijk van Doorn
  • Gunhild Waldemar
  • Anders Wallin
  • Jens Wiltfang
  • David A Wolk
  • Marzena Zboch
  • Henrik Zetterberg
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Neurology

Keywords

  • Amyloid beta-Peptides: analysis, Apolipoprotein E4: genetics, Biological Markers: analysis, Brain: pathology, Cerebrospinal Fluid: chemistry, Dementia: pathology, Mild Cognitive Impairment: pathology
Original languageEnglish
Pages (from-to)1924-1938
JournalJAMA: the journal of the American Medical Association
Volume313
Issue number19
Publication statusPublished - 2015
Publication categoryResearch
Peer-reviewedYes

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