Progress toward standardized diagnosis of vascular cognitive impairment: Guidelines from the Vascular Impairment of Cognition Classification Consensus Study

Research output: Contribution to journalArticle


Introduction: Progress in understanding and management of vascular cognitive impairment (VCI) has been hampered by lack of consensus on diagnosis, reflecting the use of multiple different assessment protocols. A large multinational group of clinicians and researchers participated in a two-phase Vascular Impairment of Cognition Classification Consensus Study (VICCCS) to agree on principles (VICCCS-1) and protocols (VICCCS-2) for diagnosis of VCI. We present VICCCS-2. Methods: We used VICCCS-1 principles and published diagnostic guidelines as points of reference for an online Delphi survey aimed at achieving consensus on clinical diagnosis of VCI. Results: Six survey rounds comprising 65–79 participants agreed guidelines for diagnosis of VICCCS-revised mild and major forms of VCI and endorsed the National Institute of Neurological Disorders–Canadian Stroke Network neuropsychological assessment protocols and recommendations for imaging. Discussion: The VICCCS-2 suggests standardized use of the National Institute of Neurological Disorders–Canadian Stroke Network recommendations on neuropsychological and imaging assessment for diagnosis of VCI so as to promote research collaboration.


  • VICCCS group
  • Olivia A. Skrobot
  • Sandra E. Black
  • Christopher Chen
  • Charles DeCarli
  • Timo Erkinjuntti
  • Gary A. Ford
  • Rajesh N. Kalaria
  • John O'Brien
  • Leonardo Pantoni
  • Florence Pasquier
  • Gustavo C. Roman
  • Anders Wallin
  • Perminder Sachdev
  • Ingmar Skoog
  • E. Englund (Contributor)
External organisations
  • University of Bristol
  • University of Toronto
  • National University of Singapore
  • University of California, Davis
  • Helsinki University Central Hospital
  • University of Oxford
  • University of Newcastle upon Tyne
  • University of Cambridge
  • University of Florence
  • University of Lille
  • Sahlgrenska University Hospital
  • Prince of Wales Hospital
  • University of Helsinki
  • Houston Methodist
  • University of Gothenburg
  • University of New South Wales
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Neurology


  • consensus, Criteria, Delphi, Guidelines, Vascular cognitive impairment, Vascular dementia
Original languageEnglish
Pages (from-to)280-292
Number of pages13
JournalAlzheimer's and Dementia
Issue number3
Publication statusPublished - 2018 Mar 1
Publication categoryResearch