Progress update from the hippocampal subfields group

Research output: Contribution to journalArticle


title = "Progress update from the hippocampal subfields group",
abstract = "Introduction: Heterogeneity of segmentation protocols for medial temporal lobe regions and hippocampal subfields on in vivo magnetic resonance imaging hinders the ability to integrate findings across studies. We aim to develop a harmonized protocol based on expert consensus and histological evidence. Methods: Our international working group, funded by the EU Joint Programme–Neurodegenerative Disease Research (JPND), is working toward the production of a reliable, validated, harmonized protocol for segmentation of medial temporal lobe regions. The working group uses a novel postmortem data set and online consensus procedures to ensure validity and facilitate adoption. Results: This progress report describes the initial results and milestones that we have achieved to date, including the development of a draft protocol and results from the initial reliability tests and consensus procedures. Discussion: A harmonized protocol will enable the standardization of segmentation methods across laboratories interested in medial temporal lobe research worldwide. {\textcopyright} 2019 The Authors",
keywords = "Cytoarchitecture, ex vivo, Hippocampus, Histology, Human, Neuroanatomy, Neuroimaging, Structural imaging, Volumetry",
author = "Olsen, {Rosanna K.} and David Berron and Wisse, {Laura E.M.} and {Hippocampal Subfields Group}",
year = "2019",
doi = "10.1016/j.dadm.2019.04.001",
language = "English",
volume = "11",
pages = "439--449",
journal = "Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring",
issn = "2352-8729",
publisher = "Elsevier",