Proliferation and benevolence—A framework for dissecting the mechanisms of microbial virulence and health promotion
Research output: Contribution to journal › Article
Key topics in the study of host–microbe interactions—such as the prevention of drug resistance and the exploitation of beneficial effects of bacteria—would benefit from concerted efforts with both mechanistic and evolutionary approaches. But due to differences in intellectual traditions, insights gained in one field rarely benefit the other. Here, we develop a conceptual and analytical framework for the integrated study of host–microbe interactions. This framework partitions the health effects of microbes and the effector molecules they produce into components with different evolutionary implications. It thereby facilitates the prediction of evolutionary responses to inhibition and exploitation of specific molecular mechanisms.
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Number of pages||10|
|Early online date||2020 Mar 14|
|Publication status||Published - 2020 May|