Proteomics: A new research area for the biomedical field

Research output: Contribution to journalArticle

Abstract

Proteomics, the detailed understanding of the role that proteins play in health and disease, is a necessary complement to genetic analysis. Rapid progress within the proteomics field has opened up possibilities for direct intervention in the medical and clinical area where diseases, disease progression and cause of disease can be investigated at a molecular level. This review introduces the proteomics field, illustrating the link to disease and organ dysfunctions, and the problem-solving progress currently ongoing in other research areas. The proteomics research field is progressing through developments in novel technology that have recently driven the biological interpretation of proteomics studies forward. A personal overview is presented with examples from the areas of clinical proteomics, tissue imaging and profiling, as well as examples of targeted proteomics studies.

Details

Authors
Organisations
External organisations
  • ETH Zürich
  • Institute for Systems Biology, Seattle
  • University of Washington
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Medical Biotechnology

Keywords

  • disease microenvironment, lung, mass spectrometry, multidimensional liquid phase separation
Original languageEnglish
Pages (from-to)83-94
Number of pages12
JournalJournal of Organ Dysfunction
Volume1
Issue number1
Publication statusPublished - 2005 Jan 1
Publication categoryResearch
Peer-reviewedYes