Proteomics: A new research area for the biomedical field

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Proteomics : A new research area for the biomedical field. / Malmström, Johan; Malmström, Lars; Marko-Varga, György.

In: Journal of Organ Dysfunction, Vol. 1, No. 1, 01.01.2005, p. 83-94.

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TY - JOUR

T1 - Proteomics

T2 - Journal of Organ Dysfunction

AU - Malmström, Johan

AU - Malmström, Lars

AU - Marko-Varga, György

PY - 2005/1/1

Y1 - 2005/1/1

N2 - Proteomics, the detailed understanding of the role that proteins play in health and disease, is a necessary complement to genetic analysis. Rapid progress within the proteomics field has opened up possibilities for direct intervention in the medical and clinical area where diseases, disease progression and cause of disease can be investigated at a molecular level. This review introduces the proteomics field, illustrating the link to disease and organ dysfunctions, and the problem-solving progress currently ongoing in other research areas. The proteomics research field is progressing through developments in novel technology that have recently driven the biological interpretation of proteomics studies forward. A personal overview is presented with examples from the areas of clinical proteomics, tissue imaging and profiling, as well as examples of targeted proteomics studies.

AB - Proteomics, the detailed understanding of the role that proteins play in health and disease, is a necessary complement to genetic analysis. Rapid progress within the proteomics field has opened up possibilities for direct intervention in the medical and clinical area where diseases, disease progression and cause of disease can be investigated at a molecular level. This review introduces the proteomics field, illustrating the link to disease and organ dysfunctions, and the problem-solving progress currently ongoing in other research areas. The proteomics research field is progressing through developments in novel technology that have recently driven the biological interpretation of proteomics studies forward. A personal overview is presented with examples from the areas of clinical proteomics, tissue imaging and profiling, as well as examples of targeted proteomics studies.

KW - disease microenvironment

KW - lung

KW - mass spectrometry

KW - multidimensional liquid phase separation

U2 - 10.1080/17471060500223910

DO - 10.1080/17471060500223910

M3 - Article

VL - 1

SP - 83

EP - 94

JO - Journal of Organ Dysfunction

JF - Journal of Organ Dysfunction

SN - 1747-1060

IS - 1

ER -