Quantitative SPECT by attenuation correction of the projection set using transmission data: evaluation of a method

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T1 - Quantitative SPECT by attenuation correction of the projection set using transmission data: evaluation of a method

AU - Almquist, Helén

AU - Palmer, John

AU - Ljungberg, Michael

AU - Wollmer, Per

AU - Strand, Sven-Erik

AU - Jonson, Björn

PY - 1990

Y1 - 1990

N2 - A method for measuring attenuation coefficients in single-photon emission tomography (SPECT) is described and evaluated, together with a method for attenuation correction using these measured attenuation coefficients. Build-up, caused by scattered photons, is corrected for by a simple substitution in the algorithms. Transmission studies are performed with a 99mTc- or 57Co flood source, and emission phantom studies with 99mTc line sources. The method is evaluated with variable but well-defined phantoms. The result is accurate attenuation coefficients for different densities, dimensions and geometries, and an accuracy of corrected emission activities of better than +/- 10% in most cases. The present limitations of the method for attenuation correction are discussed.

AB - A method for measuring attenuation coefficients in single-photon emission tomography (SPECT) is described and evaluated, together with a method for attenuation correction using these measured attenuation coefficients. Build-up, caused by scattered photons, is corrected for by a simple substitution in the algorithms. Transmission studies are performed with a 99mTc- or 57Co flood source, and emission phantom studies with 99mTc line sources. The method is evaluated with variable but well-defined phantoms. The result is accurate attenuation coefficients for different densities, dimensions and geometries, and an accuracy of corrected emission activities of better than +/- 10% in most cases. The present limitations of the method for attenuation correction are discussed.

KW - Attenuation correction

KW - Build-up

KW - Quantitative SPECT

KW - Transmission measurement

U2 - 10.1007/BF00998154

DO - 10.1007/BF00998154

M3 - Article

VL - 16

SP - 587

EP - 594

JO - European Journal of Nuclear Medicine and Molecular Imaging

JF - European Journal of Nuclear Medicine and Molecular Imaging

SN - 1619-7070

IS - 8-10

ER -