Quantitative X-ray phase-contrast computed tomography at 82 keV

Research output: Contribution to journalArticle


Potential applications of grating-based X-ray phase-contrast imaging are investigated in various fields due to its compatibility with laboratory X-ray sources. So far the method was mainly restricted to X-ray energies below 40 keV, which is too low to examine dense or thick objects, but a routine operation at higher energies is on the brink of realisation. In this study, imaging results obtained at 82 keV are presented. These comprise a test object consisting of well-defined materials for a quantitative analysis and a tooth to translate the findings to a biomedical sample. Measured linear attenuation coefficients mu and electron densities rho(e) are in good agreement with theoretical values. Improved contrast-to-noise ratios were found in phase contrast compared to attenuation contrast. The combination of both contrast modalities further enables to simultaneously assess information on density and composition of materials with effective atomic numbers (Z) over tilde > 8. In our biomedical example, we demonstrate the possibility to detect differences in mass density and calcium concentration within teeth. (C) 2013 Optical Society of America


  • Marian Willner
  • Martin Bech
  • Julia Herzen
  • Irene Zanette
  • Dieter Hahn
  • Johannes Kenntner
  • Juergen Mohr
  • Alexander Rack
  • Timm Weitkamp
  • Franz Pfeiffer
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Atom and Molecular Physics and Optics
Original languageEnglish
Pages (from-to)4155-4166
JournalOptics Express
Issue number4
Publication statusPublished - 2013
Publication categoryResearch