Questionnaire-based evaluation of sexual life after laparoscopic surgery for endometriosis: A systematic review of prospective studies

Research output: Contribution to journalArticle


Introduction: Endometriosis is a benign disease that affects women of reproductive age. Laparoscopic excision of endometriotic implants is considered one of the most effective therapeutic options. The disease and its treatment can have a major impact on psychosexual well-being but this is often overlooked as most studies focus on pain instead of sexuality in a holistic approach. The aim of this study was to review the current literature regarding the effect of laparoscopic surgery for endometriosis on quality of sexual life (QoSL). Material and methods: Following the "Preferred Reporting Items for Systematic Reviews and Meta-Analyses" guidelines we conducted a systematic review that involved searching PubMed and Embase databases for prospective studies evaluating the effect of laparoscopic surgery for endometriosis on QoSL, using validated questionnaires. Results: Of 357 papers, 17 were selected for full text evaluation. Twelve studies using seven different questionnaires fulfilled the inclusion criteria. All studies reported improvements in QoSL following laparoscopic surgery for endometriosis. A meta-analysis could not be performed due to substantial heterogeneity among the included studies arising from differences in questionnaires, follow-up duration, stages of endometriosis, use of hormonal treatment, and missing data. Conclusions: Laparoscopic excision of endometriosis can improve QoSL. However, there is a need for randomized controlled trials based on a new validated questionnaire regarding specifically QoSL in association with endometriosis. As sexual functioning is a complex phenomenon driven by multiple physical, psychological and social factors, QoSL should be holistically evaluated by a team of different healthcare providers, implementing treatment programs that are individualized to each woman.


  • Cecilie Franck
  • Marlene H. Poulsen
  • Grigorios Karampas
  • Annamaria Giraldi
  • Martin Rudnicki
External organisations
  • University of Southern Denmark
  • Skåne University Hospital
  • Odense University Hospital
  • University of Copenhagen
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Obstetrics, Gynecology and Reproductive Medicine


  • Endometriosis, Laparoscopy, Questionnaire, Sexual function, Systematic review
Original languageEnglish
JournalActa Obstetricia et Gynecologica Scandinavica
Publication statusE-pub ahead of print - 2018 Jan 1
Publication categoryResearch
Externally publishedYes