Real-life assessment of chronic rhinosinusitis patients using mobile technology: The mySinusitisCoach project by EUFOREA

Research output: Contribution to journalArticle

Abstract

Background: Chronic rhinosinusitis (CRS) is a chronic inflammatory disease associated with a substantial personal and socioeconomic burden. Monitoring of patient-reported outcomes by mobile technology offers the possibility to better understand real-life burden of CRS. Methods: This study reports on the cross-sectional evaluation of data of 626 users of mySinusitisCoach (mSC), a mobile application for CRS patients. Patient characteristics of mSC users were analysed as well as the level of disease control based on VAS global rhinosinusitis symptom score and adapted EPOS criteria. Results: The mSC cohort represents a heterogeneous group of CRS patients with a diverse pattern of major symptoms. Approximately half of patients reported nasal polyps. 47.3% of all CRS patients were uncontrolled based on evaluation of VAS global rhinosinusitis symptom score compared to 40.9% based on adapted EPOS criteria. The impact of CRS on sleep quality and daily life activities was significantly higher in uncontrolled versus well-controlled patients. Half of patients had a history of FESS (functional endoscopic sinus surgery) and reported lower symptom severity compared to patients without a history of FESS, except for patients with a history of more than 3 procedures. Patients with a history of FESS reported higher VAS levels for impaired smell. Conclusion: Real-life data confirm the high disease burden in uncontrolled CRS patients, clearly impacting quality of life. Sinus surgery improves patient-reported outcomes, but not in patients with a history of more than 3 procedures. Mobile technology opens a new era of real-life monitoring, supporting the evolution of care towards precision medicine.

Details

Authors
  • Sven F. Seys
  • Shana De Bont
  • Wytske J. Fokkens
  • Claus Bachert
  • Isam Alobid
  • Manuel Bernal-Sprekelsen
  • Ina Callebaut
  • Lars Olaf Cardell
  • Sean Carrie
  • Paolo Castelnuovo
  • Russell Cathcart
  • Jannis Constantinidis
  • Leen Cools
  • Marjolein Cornet
  • Gregory Clement
  • Tony Cox
  • Lieve Delsupehe
  • Jaime Correia-de-Sousa
  • Lauren Deneyer
  • Geert De Vos
  • Zuzana Diamant
  • Maria Doulaptsi
  • Simon Gane
  • Philippe Gevaert
  • Claire Hopkins
  • Valérie Hox
  • Thomas Hummel
  • Werner Hosemann
  • Raf Jacobs
  • Mark Jorissen
  • Anette Kjeldsen
  • Basile N. Landis
  • Winde Lemmens
  • Andreas Leunig
  • Valerie Lund
  • Gert Mariën
  • Joaquim Mullol
  • Metin Onerci
  • Susanna Palkonen
  • Isabel Proano
  • Emmanuel Prokopakis
  • Dermot Ryan
  • Herbert Riechelmann
  • Sanna Salmi-Toppila
  • Christine Segboer
  • Kato Speleman
  • Andreas Steinsvik
  • Pavol Surda
  • Peter Valentin Tomazic
  • Olivier Vanderveken
  • Laura Van Gerven
  • Thibaut Van Zele
  • Jan Verfaillie
  • Benedicte Verhaeghe
  • Kathie Vierstraete
  • Stephan Vlaminck
  • Martin Wagenmann
  • Benoit Pugin
  • Peter W. Hellings
Organisations
External organisations
  • European Forum for Research and Education in Allergy and Airway diseases (EUFOREA)
  • Catholic University of Leuven
  • University Hospitals Leuven
  • Academic Medical Center of University of Amsterdam (AMC)
  • Ghent University
  • Karolinska Institutet
  • University of Barcelona
  • University of Valencia
  • Freeman Hospital
  • University of Insubria
  • Cumberland Infirmary
  • Aristotle University of Thessaloniki
  • Algemeen Ziekenhuis Damiaan Oostende
  • Jessa Hospital
  • AZ Delta
  • University of Minho
  • General Hospital Sint-Lucas
  • University Medical Center Groningen
  • Charles University in Prague
  • University of Crete Medical School
  • Royal National Throat, Nose and Ear Hospital
  • Guy's and St Thomas' NHS Foundation Trust
  • Saint-Luc University Hospital
  • Dresden University of Technology
  • University of Greifswald
  • General Hospital Sint-Blasius
  • Odense University Hospital
  • Geneva University Hospital
  • Hospital Oost-Limburg
  • World Orthopaedic Concern
  • Hacettepe University
  • EFA European Federation of Allergy and Airways Diseases Patients' Associations
  • University of Edinburgh
  • Medical University of Innsbruck
  • Skin and Allergy Hospital
  • University of Helsinki Haartman Institute
  • General Hospital St. Jan
  • Akershus University Hospital
  • Medical University of Graz
  • Antwerp University Hospital
  • Sint Andries Hospital
  • Algemeen Ziekenhuis Groeninge
  • Universitätsklinikum Düsseldorf
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Respiratory Medicine and Allergy

Keywords

  • Mobile health technology, nasal polyp, patient-reported outcome measure, real-world evidence, visual analogue scale
Original languageEnglish
Pages (from-to)2867-2878
Number of pages12
JournalAllergy: European Journal of Allergy and Clinical Immunology
Volume75
Issue number11
Publication statusPublished - 2020 Nov 1
Publication categoryResearch
Peer-reviewedYes