Recommendations for Core Outcome Domain Set for Whiplash Associated Disorders (CATWAD)

Research output: Contribution to journalArticle

Abstract

Objective: Inconsistent reporting of outcomes in clinical trials of treatments for Whiplash Associated Disorders (WAD) hinders effective data pooling and conclusions that can be drawn about the effectiveness of tested treatments. The aim of this study was to provide recommendations for core outcome domains that should be included in clinical trials of WAD. Methods: A three-step process was used. 1) A list of potential core outcome domains were identified from the published literature; 2) Researchers, health care providers, patients and insurance personnel participated and rated the importance of each domain via a three round Delphi survey. A priori criteria for consensus were established; 3) Experts comprising researchers, health care providers and a consumer representative participated in a multidisciplinary consensus meeting that made final decisions on the recommended core outcome domains. Results: The literature search identified 63 potential core domains. 223 participants were invited to partake in the Delphi surveys with 41.7% completing Round 1, 45.3% Round 2 and 51.4% Round 3. Eleven core domains met the criteria for inclusion across the entire sample. After the expert consensus meeting, six core domains were recommended: Physical Functioning, Perceived Recovery, Work and Social Functioning, Psychological Functioning, Quality of Life and Pain. Discussion: A 3-step process was used to recommend core outcome domains for clinical trials in WAD. Six core domains were recommended: Physical Functioning, Perceived Recovery, Work and Social Functioning, Psychological Functioning, Quality of Life and Pain. The next step is to determine the outcome measurement instruments for each of these domains.

Details

Authors
  • Kenneth Chen
  • Tonny Andersen
  • Linda Carroll
  • Luke Connelly
  • Pierre Côté
  • Michele Curatolo
  • James Elliott
  • Genevieve Grant
  • Gwendolen Jull
  • Helge Kasch
  • Joy MacDermid
  • Eva Maj Malmström
  • Annick Maujean
  • Samuel A. McLean
  • Mandy Nielsen
  • Trudy Rebbeck
  • Anne Söderlund
  • Joanna Sterling
  • Julia Treleaven
  • David M. Walton
  • And 2 others
  • Hans Westergren
  • Michele Sterling
Organisations
External organisations
  • University of Queensland
  • Griffith University
  • University of Southern Denmark
  • University of Alberta
  • University of Washington
  • Northwestern University Feinberg School of Medicine
  • Monash University
  • Aarhus University
  • University of North Carolina
  • Mälardalen University
  • University of Western Ontario
  • University of Ontario Institute of Technology
  • Skåne University Hospital
  • Chronic Pain Australia
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Physiotherapy
  • Health Care Service and Management, Health Policy and Services and Health Economy

Keywords

  • domains, neck, outcome, pain, whiplash
Original languageEnglish
Pages (from-to)727-736
JournalClinical Journal of Pain
Volume35
Issue number9
Early online date2019
Publication statusPublished - 2019
Publication categoryResearch
Peer-reviewedYes