Re-evaluation of classical prognostic factors in resectable ductal adenocarcinoma of the pancreas

Research output: Contribution to journalArticle

Abstract

Pancreatic ductal adenocarcinoma carries a poor prognosis with annual deaths almost matching the reported incidence rates. Surgical resection offers the only potential cure. Yet, even among patients that undergo tumor resection, recurrence rates are high and long-term survival is scarce. Various tumorrelated factors have been identified as predictors of survival after potentially curative resection. These factors include tumor size, lymph node disease, tumor grade, vascular invasion, perineural invasion and surgical resection margin. This article will re-evaluate the importance of these factors based on recent publications on the topic, with potential implications for treatment and outcome in patients with pancreatic cancer.

Details

Authors
Organisations
External organisations
  • Skåne University Hospital
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Cancer and Oncology

Keywords

  • Pancreatic cancer, Prognostic factors, Survival
Original languageEnglish
Pages (from-to)6424-6433
Number of pages10
JournalWorld Journal of Gastroenterology
Volume22
Issue number28
Publication statusPublished - 2016 Jul 28
Publication categoryResearch
Peer-reviewedYes