Regional tissue metabolism during open or endovascular abdominal aortic aneurysm surgery

Research output: Contribution to journalArticle


Objective: to investigate differences in regional tissue metabolism between open and endovascular aneurysm repair utilising a microdialysis technique. Materials: eight patients receiving endovascular stent grafts (STENT) and six patients undergoing open aortic surgery (OPEN) for abdominal aortic aneurysms were studied prospectively but non-randomised. Method: microdialysis catheters placed subcutaneously in the pectoral and calf region, respectively. Results: microdialysate glucose levels increased in the OPEN group on the day of surgery. Microdialysate lactate levels increased transiently in the leg in the STENT group. In the OPEN group lactate increased in the leg after aortic cross-clamping. Glycerol decreased in the pectoral region in the STENT group after surgery, but remained elevated in the OPEN group. Conclusion: we found indications that the metabolic impact of the two aortic procedures differ. This may be of clinical importance when selecting patients for either open aortic surgery or endovascular stentgrafting.


  • Carsten Metzsch
  • Johan Lundberg
  • Lars Norgren
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Surgery


  • Endovascular surgery, Vascular surgery, Adipose tissue metabolism, Microdialysis
Original languageEnglish
Pages (from-to)320-325
JournalEuropean Journal of Vascular and Endovascular Surgery
Issue number4
Publication statusPublished - 2001
Publication categoryResearch

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Anaesthesiology and Intensive Care (Mö) (013241110), Anaesthesiology and Intensive Care (013230022), Emergency medicine/Medicine/Surgery (013240200)