Registries on peritoneal surface malignancies throughout the world, their use and their options

Research output: Contribution to journalArticle

Abstract

Aim: The treatment of peritoneal surface malignancies ranges from palliative care to full cytoreductive surgery (CRS) and heated intraperitoneal chemotherapy, HIPEC. Ongoing monitoring of patient recruitment and volume is usually carried out through dedicated registries. With multiple registries available worldwide, we sought to investigate the nature, extent and value of existing worldwide CRS and HIPEC registries. Methods: A questionnaire was sent out to all known major treatment centres. The questionnaire covers: general purpose of the registry; inclusion criteria in the registry; the date the registry was first established; volume of patients in the registry and description of the data fields in the registries. Finally, the population size of the catchment area of the registry was collected. Results: Twenty-seven questionnaires where returned. National databases are established in northwest European countries. There are five international general databases. Most database collect data on patients who have undergone an attempt to CRS and HIPEC. Two registries collect data on all patients with peritoneal carcinomatosis regardless the treatment. Most registries are primarily used for tracking outcomes and complications. When correlating the number of cases of CRS and HIPEC that are performed to the catchment area of the various registry, a large variation in the number of performed procedures related to the overall population was noted, ranging from 1.3 to 57 patients/million year with an average of 15 patients/1 million year. Conclusions: CRS and HIPEC is a well-established treatment for peritoneal surface malignancies worldwide. However, the coverage as well as the registration of treatment procedures differs widely. The most striking difference is the proportion of HIPEC procedures per capita which ranges from 1.3 to 57 patients per million. This suggests either a difference in patient selection, lack of access to HIPEC centres or lack of appropriate data collection.

Details

Authors
  • Victor J. Verwaal
  • Beate Rau
  • Faek Jamali
  • François Noël Gilly
  • Ignace de Hingh
  • Heikki Takala
  • Ingvar Syk
  • Jorg Pelz
  • Jurgen Mulsow
  • Kurt van der Speeten
  • Kusamura Shigeki
  • Lene H. Iversen
  • Faheez Mohamed
  • Olivier Glehen
  • Rami Younan
  • Roman Yarema
  • Santiago Gonzalez-Moreno
  • Sarah O’Dwyer
  • Yukata Yonemura
  • Paul Sugarbaker
Organisations
External organisations
  • Charité - University Medicine Berlin
  • American University of Beirut
  • Oulu University Hospital
  • Hospital Oost-Limburg
  • Great Ormond Street Hospital
  • Claude Bernard University Lyon 1
  • Catharina Hospital
  • University Hospital of Wϋrzburg
  • Mater Misericordiae University Hospital
  • Istituto Nazionale dei Tumori
  • Aarhus University Hospital
  • North Hampshire Hospital
  • Clinique Médicale Agatha
  • Danylo Halytsky Lviv National Medical University
  • MD Anderson Cancer Center Madrid
  • NPO organization to Support Peritoneal Dissemination Treatment
  • MedStar Washington Hospital Center
Research areas and keywords

Keywords

  • HIPEC, peritoneal surface malignancy, registration study
Original languageEnglish
Pages (from-to)528-533
Number of pages6
JournalInternational Journal of Hyperthermia
Volume33
Issue number5
Publication statusPublished - 2017 Jul 4
Publication categoryResearch
Peer-reviewedYes