Reovirus type 1 associated with meningitis

Research output: Contribution to journalArticle


title = "Reovirus type 1 associated with meningitis",
abstract = "A previously healthy 3-month-old girl presented with symptoms of meningitis, diarrhoea, vomiting and fever. Green monkey kidney (GMK) cells inoculated with cerebrospinal fluid (CSF) revealed reovirus-like particles by electron microscopy. RNA-gel electrophoresis, immunofluorescence and virus neutralization identified the pathogen isolated from CSF as reovirus type 1. Antibody determination by immunofluorescence of paired sera showed a significant antibody titre rise to the CSF isolate and neutralization test revealed a greater than 4-fold antibody titre rise to the CSF isolate. The CSF isolate was also neutralized by reovirus type 1 antibodies. This report represents one of a few associating reovirus with CNS symptoms in humans.",
author = "Hugo Johansson and Tomas Sveger and Karin Ahlfors and Jarl Ekstrand and Lennart Svensson",
year = "1996",
doi = "10.3109/00365549609049060",
language = "English",
volume = "28",
pages = "117--120",
journal = "Scandinavian Journal of Infectious Diseases",
issn = "1651-1980",
publisher = "Informa Healthcare",
number = "2",