Reply to letter by Deng et al. "Could the levels of inflammation biomarkers predict OA? Comment on the article by Roemer FW et al."

Research output: Contribution to journalLetter


As explained in the methods-section, we chose to analyze the 2-year data in regard to inflammatory activity based on MRI and synovial biomarkers (and not earlier time points) as our aim was to capture patients that experienced "prolonged" or chronic inflammation, which may be regarded as a potential risk factor for osteoarthritis (OA) development. Virtually all patients of an acute injury cohort (like the KANON patients) will exhibit acute post-traumatic inflammation in their injured knee to a various extent as manifested by marked changes on imaging (i.e. effusion, traumatic synovitis and haemarthrosis) or in biochemical parameters. This article is protected by copyright. All rights reserved.


External organisations
  • University Hospital Erlangen
  • Boston University
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Rheumatology and Autoimmunity
Original languageEnglish
JournalArthritis & Rheumatology
Publication statusE-pub ahead of print - 2019 May 23
Publication categoryResearch

Bibliographic note

This article is protected by copyright. All rights reserved.