REPRESENTATIVE SELECTION OF PROTEINS BASED ON NUCLEAR FAMILIES

Research output: Contribution to journalLetter

Abstract

The selection of unbiased representatives from a large database is complicated by the requirement for the chosen entries to be not only genuinely different from each other but also typical for the family of related entries. A method satisfying this 2-fold objective was developed by equipping complete linkage clustering with a novel noise elimination procedure to deal with overlapping cluster structure, A total of 200 nuclear families of truly related Brookhaven Protein Data Bank structures were generated, from which any entry can be chosen to represent its family.

Details

Authors
External organisations
  • External Organization - Unknown
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Medical Genetics

Keywords

  • COMPLETE LINKAGE CLUSTERING, NOISE ELIMINATION, PDB FAMILIES, REPRESENTATIVE SELECTION
Original languageEnglish
Pages (from-to)501-503
JournalProtein Engineering
Volume8
Issue number5
Publication statusPublished - 1995
Publication categoryResearch
Peer-reviewedYes
Externally publishedYes