REPRESENTATIVE SELECTION OF PROTEINS BASED ON NUCLEAR FAMILIES

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REPRESENTATIVE SELECTION OF PROTEINS BASED ON NUCLEAR FAMILIES. / BOBERG, J; SALAKOSKI, T; Vihinen, Mauno.

In: Protein Engineering, Vol. 8, No. 5, 1995, p. 501-503.

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BOBERG, J ; SALAKOSKI, T ; Vihinen, Mauno. / REPRESENTATIVE SELECTION OF PROTEINS BASED ON NUCLEAR FAMILIES. In: Protein Engineering. 1995 ; Vol. 8, No. 5. pp. 501-503.

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TY - JOUR

T1 - REPRESENTATIVE SELECTION OF PROTEINS BASED ON NUCLEAR FAMILIES

AU - BOBERG, J

AU - SALAKOSKI, T

AU - Vihinen, Mauno

PY - 1995

Y1 - 1995

N2 - The selection of unbiased representatives from a large database is complicated by the requirement for the chosen entries to be not only genuinely different from each other but also typical for the family of related entries. A method satisfying this 2-fold objective was developed by equipping complete linkage clustering with a novel noise elimination procedure to deal with overlapping cluster structure, A total of 200 nuclear families of truly related Brookhaven Protein Data Bank structures were generated, from which any entry can be chosen to represent its family.

AB - The selection of unbiased representatives from a large database is complicated by the requirement for the chosen entries to be not only genuinely different from each other but also typical for the family of related entries. A method satisfying this 2-fold objective was developed by equipping complete linkage clustering with a novel noise elimination procedure to deal with overlapping cluster structure, A total of 200 nuclear families of truly related Brookhaven Protein Data Bank structures were generated, from which any entry can be chosen to represent its family.

KW - COMPLETE LINKAGE CLUSTERING

KW - NOISE ELIMINATION

KW - PDB FAMILIES

KW - REPRESENTATIVE SELECTION

U2 - 10.1093/protein/8.5.501

DO - 10.1093/protein/8.5.501

M3 - Letter

VL - 8

SP - 501

EP - 503

JO - Protein Engineering, Design and Selection

T2 - Protein Engineering, Design and Selection

JF - Protein Engineering, Design and Selection

SN - 1741-0126

IS - 5

ER -