Resistance to phagocytosis in Streptococcus pyogenes

Research output: ThesisDoctoral Thesis (compilation)

Abstract

Phagocytosis of Streptococcus pyogenes is complement dependent. However, the cell wall-associated M protein, which exists in >100 different serotypes (M types), enables the bacteria to evade phagocytosis. To analyze the mechanisms by which M protein confers this ability we used, as model systems, two representative M proteins, the M22 and M5 proteins, which have properties typical for many M proteins of different M type.

Details

Authors
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Microbiology in the medical area

Keywords

  • Infektioner, Infections, Medicine (human and vertebrates), Medicin (människa och djur), phagocytosis, innate immunity, complement, Streptococcus pyogenes, M protein
Original languageEnglish
QualificationDoctor
Awarding Institution
Supervisors/Assistant supervisor
Award date2005 May 21
Publisher
  • Department of Laboratory Medicine, Lund University
Print ISBNs91-85439-38-X
Publication statusPublished - 2005
Publication categoryResearch

Bibliographic note

Defence details Date: 2005-05-21 Time: 09:30 Place: Segerfalkssalen External reviewer(s) Name: Wessels, Michael R. Title: professor Affiliation: Harvad Medical School ---