Reversal of status dystonicus after relocation of pallidal electrodes in DYT6 generalized dystonia

Research output: Contribution to journalArticle

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Reversal of status dystonicus after relocation of pallidal electrodes in DYT6 generalized dystonia. / Oterdoom, D. L.Marinus; Van Egmond, Martje E.; Ascencao, Luisa Cassini; Van Dijk, J. Marc C.; Saryyeva, Assel; Beudel, Martijn; Runge, Joachim; de Koning, Tom J.; Abdallat, Mahmoud; Eggink, Hendriekje; Tijssen, Marina A.J.; Krauss, Joachim K.

In: Tremor and Other Hyperkinetic Movements, Vol. 8, 530, 2018, p. 1-4.

Research output: Contribution to journalArticle

Harvard

Oterdoom, DLM, Van Egmond, ME, Ascencao, LC, Van Dijk, JMC, Saryyeva, A, Beudel, M, Runge, J, de Koning, TJ, Abdallat, M, Eggink, H, Tijssen, MAJ & Krauss, JK 2018, 'Reversal of status dystonicus after relocation of pallidal electrodes in DYT6 generalized dystonia', Tremor and Other Hyperkinetic Movements, vol. 8, 530, pp. 1-4. https://doi.org/10.5334/TOHM.409

APA

Oterdoom, D. L. M., Van Egmond, M. E., Ascencao, L. C., Van Dijk, J. M. C., Saryyeva, A., Beudel, M., Runge, J., de Koning, T. J., Abdallat, M., Eggink, H., Tijssen, M. A. J., & Krauss, J. K. (2018). Reversal of status dystonicus after relocation of pallidal electrodes in DYT6 generalized dystonia. Tremor and Other Hyperkinetic Movements, 8, 1-4. [530]. https://doi.org/10.5334/TOHM.409

CBE

Oterdoom DLM, Van Egmond ME, Ascencao LC, Van Dijk JMC, Saryyeva A, Beudel M, Runge J, de Koning TJ, Abdallat M, Eggink H, Tijssen MAJ, Krauss JK. 2018. Reversal of status dystonicus after relocation of pallidal electrodes in DYT6 generalized dystonia. Tremor and Other Hyperkinetic Movements. 8:1-4. https://doi.org/10.5334/TOHM.409

MLA

Vancouver

Author

Oterdoom, D. L.Marinus ; Van Egmond, Martje E. ; Ascencao, Luisa Cassini ; Van Dijk, J. Marc C. ; Saryyeva, Assel ; Beudel, Martijn ; Runge, Joachim ; de Koning, Tom J. ; Abdallat, Mahmoud ; Eggink, Hendriekje ; Tijssen, Marina A.J. ; Krauss, Joachim K. / Reversal of status dystonicus after relocation of pallidal electrodes in DYT6 generalized dystonia. In: Tremor and Other Hyperkinetic Movements. 2018 ; Vol. 8. pp. 1-4.

RIS

TY - JOUR

T1 - Reversal of status dystonicus after relocation of pallidal electrodes in DYT6 generalized dystonia

AU - Oterdoom, D. L.Marinus

AU - Van Egmond, Martje E.

AU - Ascencao, Luisa Cassini

AU - Van Dijk, J. Marc C.

AU - Saryyeva, Assel

AU - Beudel, Martijn

AU - Runge, Joachim

AU - de Koning, Tom J.

AU - Abdallat, Mahmoud

AU - Eggink, Hendriekje

AU - Tijssen, Marina A.J.

AU - Krauss, Joachim K.

PY - 2018

Y1 - 2018

N2 - Background: DYT6 dystonia can have an unpredictable clinical course and the result of deep brain stimulation (DBS) of the internal part of the globus pallidus (GPi) is known to be less robust than in other forms of autosomal dominant dystonia. Patients who had previous stereotactic surgery with insufficient clinical benefit form a particular challenge with very limited other treatment options available. Case Report: A pediatric DYT6 patient unexpectedly deteriorated to status dystonicus 1 year after GPi DBS implantation with good initial clinical response. After repositioning the DBS electrodes the status dystonicus resolved. Discussion: This case study demonstrates that medication-resistant status dystonicus in DYT6 dystonia can be reversed by relocation of pallidal electrodes. This case highlights that repositioning of DBS electrodes may be considered in patients with status dystonicus, especially when the electrode position is not optimal, even after an initial clinical response to DBS.

AB - Background: DYT6 dystonia can have an unpredictable clinical course and the result of deep brain stimulation (DBS) of the internal part of the globus pallidus (GPi) is known to be less robust than in other forms of autosomal dominant dystonia. Patients who had previous stereotactic surgery with insufficient clinical benefit form a particular challenge with very limited other treatment options available. Case Report: A pediatric DYT6 patient unexpectedly deteriorated to status dystonicus 1 year after GPi DBS implantation with good initial clinical response. After repositioning the DBS electrodes the status dystonicus resolved. Discussion: This case study demonstrates that medication-resistant status dystonicus in DYT6 dystonia can be reversed by relocation of pallidal electrodes. This case highlights that repositioning of DBS electrodes may be considered in patients with status dystonicus, especially when the electrode position is not optimal, even after an initial clinical response to DBS.

KW - deep brain stimulation

KW - DYT6

KW - Status dystonicus

U2 - 10.5334/TOHM.409

DO - 10.5334/TOHM.409

M3 - Article

C2 - 29520331

AN - SCOPUS:85051759877

VL - 8

SP - 1

EP - 4

JO - Tremor and Other Hyperkinetic Movements

JF - Tremor and Other Hyperkinetic Movements

SN - 2160-8288

M1 - 530

ER -