Review of life science applications using submicron O-PTIR and simultaneous Raman microscopy: a new paradigm in vibrational spectroscopy
Research output: Contribution to journal › Review article
The recent advent of Optical Photothermal IR (O-PTIR), has enabled for the first time, submicron infrared microscopy in far-field reflection mode with the combination of Raman for simultaneous, correlative IR+Raman microscopy. These unique and exciting synergistic capabilities are now spawning interest in life science application. A broad range of life science applications, otherwise impossible with traditional FTIR/QCL microscopy, will be presented, ranging from live cell imaging in water, to ultra-high resolution images of breast tissue calcifications, amyloid aggregates in neurons (neurites and dendritic spines), individual collagen fibrils with polarized IR and individual isotopically labelled bacterial cells and more.
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Journal||Advanced Chemical Microscopy for Life Science and Translational Medicine|
|Publication status||Published - 2021 Mar 5|
|Event||SPIE BIOS - |
Duration: 2021 Mar 6 → 2021 Apr 12
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