RIFM fragrance ingredient safety assessment, allyl (cyclohexyloxy)acetate, CAS registry number 68901-15-5.

Research output: Contribution to journalArticle

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RIFM fragrance ingredient safety assessment, allyl (cyclohexyloxy)acetate, CAS registry number 68901-15-5. / Api, A M; Belsito, D; Bhatia, S; Bruze, Magnus; Calow, P; Dagli, M L; Dekant, W; Fryer, A D; Kromidas, L; Cava, S LA; Lalko, J F; Lapczynski, A; Liebler, D C; Miyachi, Y; Politano, V T; Ritacco, G; Salvito, D; Shen, J; Schultz, T W; Sipes, I G; Wall, B; Wilcox, D K.

In: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2015.

Research output: Contribution to journalArticle

Harvard

Api, AM, Belsito, D, Bhatia, S, Bruze, M, Calow, P, Dagli, ML, Dekant, W, Fryer, AD, Kromidas, L, Cava, SLA, Lalko, JF, Lapczynski, A, Liebler, DC, Miyachi, Y, Politano, VT, Ritacco, G, Salvito, D, Shen, J, Schultz, TW, Sipes, IG, Wall, B & Wilcox, DK 2015, 'RIFM fragrance ingredient safety assessment, allyl (cyclohexyloxy)acetate, CAS registry number 68901-15-5.', Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. https://doi.org/10.1016/j.fct.2015.03.016

APA

CBE

Api AM, Belsito D, Bhatia S, Bruze M, Calow P, Dagli ML, Dekant W, Fryer AD, Kromidas L, Cava SLA, Lalko JF, Lapczynski A, Liebler DC, Miyachi Y, Politano VT, Ritacco G, Salvito D, Shen J, Schultz TW, Sipes IG, Wall B, Wilcox DK. 2015. RIFM fragrance ingredient safety assessment, allyl (cyclohexyloxy)acetate, CAS registry number 68901-15-5. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. https://doi.org/10.1016/j.fct.2015.03.016

MLA

Vancouver

Author

Api, A M ; Belsito, D ; Bhatia, S ; Bruze, Magnus ; Calow, P ; Dagli, M L ; Dekant, W ; Fryer, A D ; Kromidas, L ; Cava, S LA ; Lalko, J F ; Lapczynski, A ; Liebler, D C ; Miyachi, Y ; Politano, V T ; Ritacco, G ; Salvito, D ; Shen, J ; Schultz, T W ; Sipes, I G ; Wall, B ; Wilcox, D K. / RIFM fragrance ingredient safety assessment, allyl (cyclohexyloxy)acetate, CAS registry number 68901-15-5. In: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2015.

RIS

TY - JOUR

T1 - RIFM fragrance ingredient safety assessment, allyl (cyclohexyloxy)acetate, CAS registry number 68901-15-5.

AU - Api, A M

AU - Belsito, D

AU - Bhatia, S

AU - Bruze, Magnus

AU - Calow, P

AU - Dagli, M L

AU - Dekant, W

AU - Fryer, A D

AU - Kromidas, L

AU - Cava, S LA

AU - Lalko, J F

AU - Lapczynski, A

AU - Liebler, D C

AU - Miyachi, Y

AU - Politano, V T

AU - Ritacco, G

AU - Salvito, D

AU - Shen, J

AU - Schultz, T W

AU - Sipes, I G

AU - Wall, B

AU - Wilcox, D K

PY - 2015

Y1 - 2015

N2 - The use of this material under current use conditions is supported by the existing information. This material was evaluated for Genotoxicity, Repeated Dose Toxicity, Developmental Toxicity, Reproductive Toxicity, Local Respiratory Toxicity, Phototoxicity, Skin Sensitization potential as well as Environmental assessment. Repeated dose toxicity was determined to have the most conservative systemic exposure derived NO[A]EL of 7.5 mg/kg/day, based on a gavage reproduction dosage-range finding study conducted in rats on a read across analog, that resulted in a MOE of 441 considering 100% absorption from skin contact and inhalation. A MOE of >100 is deemed acceptable.

AB - The use of this material under current use conditions is supported by the existing information. This material was evaluated for Genotoxicity, Repeated Dose Toxicity, Developmental Toxicity, Reproductive Toxicity, Local Respiratory Toxicity, Phototoxicity, Skin Sensitization potential as well as Environmental assessment. Repeated dose toxicity was determined to have the most conservative systemic exposure derived NO[A]EL of 7.5 mg/kg/day, based on a gavage reproduction dosage-range finding study conducted in rats on a read across analog, that resulted in a MOE of 441 considering 100% absorption from skin contact and inhalation. A MOE of >100 is deemed acceptable.

U2 - 10.1016/j.fct.2015.03.016

DO - 10.1016/j.fct.2015.03.016

M3 - Article

JO - Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

T2 - Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

JF - Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

SN - 1873-6351

ER -