RIFM fragrance ingredient safety assessment, l-Borneol, CAS registry number 464-45-9.
Research output: Contribution to journal › Article
The use of this material under current use conditions is supported by the existing information. This material was evaluated for Genotoxicity, Repeated Dose Toxicity, Developmental Toxicity, Reproductive Toxicity, Local Respiratory Toxicity, Phototoxicity, Skin Sensitization potential as well as Environmental assessment. Repeated Dose Toxicity was determined using read across analog to have the most conservative systemic exposure derived NO[A]EL of 15 mg/kg/day, based on a gavage 13-week subchronic toxicity study conducted in rats, that resulted in a MOE of 3061, considering 100% absorption from skin contact and inhalation. A MOE of >100 is deemed acceptable.
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Journal||Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association|
|Early online date||2015 Apr 16|
|Publication status||Published - 2015|