Role of (p)ppGpp in biofilm formation by E. faecalis.

Research output: Contribution to journalArticle


Enterococcus faecalis strain OG1RF and its (p)ppGpp-deficient mutants ΔrelA, ΔrelQ and ΔrelAΔrelQ were grown in biofilms and evaluated for growth profiles, biofilm morphology, cell viability, and proteolytic activity. E. faecalis lacking (p)ppGpp had a diminished capacity to sustain biofilm formation over an extended period of time, and expressed abundant proteolytic activity.


  • Luis E Chávez de Paz
  • José A Lemos
  • Claes Wickström
  • Christine M Sedgley
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Cell and Molecular Biology
Original languageEnglish
JournalApplied and Environmental Microbiology
Early online date2011 Dec 16
Publication statusPublished - 2011
Publication categoryResearch

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Mucosal biology (013212033)