Ruling out risks in medical research

Research output: Contribution to journalArticle

Abstract

In medical research, it is not unusual that risks are ruled out without any specification the exact risk that was ruled out. This makes it difficult to balance expected health benefits and risk of harm when choosing between alternative treatment options. International guidelines for reporting medical research results are sufficiently specific when it comes to establishing health benefits. However, there is a lack of standards for reporting on ruling out risks. We argue that transparency is needed, as in the case of non-inferiority trials. The Consolidated Standards of Reporting Trials and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statements should be revised accordingly.

Details

Authors
Organisations
External organisations
  • Karolinska Institutet
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Medical Ethics
  • Philosophy

Keywords

  • Ruling out risks, Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), value judgment, transparency, risk margin, Consolidated Standards of Reporting Trials (CONSORT)
Original languageEnglish
Pages (from-to)796-802
JournalJournal of Risk Research
Volume22
Issue number6
Early online date2019 Mar 20
Publication statusPublished - 2019
Publication categoryResearch
Peer-reviewedYes

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