Season-dependent associations of circadian rhythm-regulating loci (CRY1, CRY2 and MTNR1B) and glucose homeostasis: the GLACIER Study.

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Abstract

The association of single nucleotide polymorphisms (SNPs) proximal to CRY2 and MTNR1B with fasting glucose is well established. CRY1/2 and MTNR1B encode proteins that regulate circadian rhythmicity and influence energy metabolism. Here we tested whether season modified the relationship of these loci with blood glucose concentration.

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  • Endocrinology and Diabetes
Original languageEnglish
Pages (from-to)997-1005
JournalDiabetologia
Volume58
Issue number5
Publication statusPublished - 2015
Publication categoryResearch
Peer-reviewedYes