Sensor Array Composed of "Clicked" Individual Microcantilever Chips

Research output: Contribution to journalArticle


A simple technique is described to functionalize a small library of microcantilever (MC) chips presenting varied headgroups. A generic azide monolayer, bound to the MC surface, can be coupled with various alkynes using efficient "click" chemistry. This method is compatible with many functional groups, and novel headgroups are introduced on the MC surface by means of alkynes synthesized via a one-step reaction. The surface "click" reaction reduces greatly the effort that would be required to synthesize and purify the corresponding functional thiols. This technique represents a convenient complementary tool for Phase-Shifting Interferometric Microscopy (PSIM) read-out that has been developed in our group. The affinity of these surface coatings towards different solvents can be estimated by measuring the deflection of the cantilevers. A proof-of-concept sensor composed of four individual MC chips presenting different headgroups can unambiguously discriminate the fingerprint response of a nerve-gas simulant from other solvent vapors.


  • Francois Paoloni
  • Sven Kelling
  • Juzheng Huang
  • Stephen R. Elliott
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Chemical Sciences
Original languageEnglish
Pages (from-to)372-379
JournalAdvanced Functional Materials
Issue number2
Publication statusPublished - 2011
Publication categoryResearch

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Polymer and Materials Chemistry (LTH) (011001041)