Serum concentrations of perfluorinated alkyl acids and their associations with diet and personal characteristics among Swedish adults

Research output: Contribution to journalArticle

Abstract

ScopeIn this study, food is suggested as a major source of human exposure to perfluorinated alkyl acids (PFAA). We investigated relations between serum levels of PFAA in adults and diet/lifestyle factors nationwide in Sweden. Methods and resultsIn 2010-2011, adults (18-80 years, N = 270) recorded their diet for 4 days and answered a food frequency questionnaire. PFAA were measured in blood serum as well as v-3 fatty acids in plasma phospholipids as a biomarker for fish consumption. Higher levels of PFAA were associated with male sex, increased age, and higher education. Women reporting full breastfeeding for 12 months had 32-44% lower levels of perfluorooctane sulfonate, perfluorooctanoic acid, and perfluorohexane sulfonate than women who never nursed their infants full-time. Serum perfluorooctane sulfonate, perfluorononanoic acid, perfluorodecanoic acid, and perfluoroundecanoic acid were positively related to n-3 fatty acids in plasma (partial r = 0.19-0.34, p 0.05). ConclusionThe relatively strong correlations between biomarkers of fish consumption and certain PFAA suggest that PFAA exposure should be taken into account in health risk and benefit assessment of fish consumption. Breastfeeding appears to be a major source of elimination of certain PFAA among women, and consequently PFAA exposure of nursed infants could be significant.

Details

Authors
  • Helena Bjermo
  • Per Ola Darnerud
  • Monika Pearson
  • Helene Enghardt Barbieri
  • Anna Karin Lindroos
  • Cecilia Nalsen
  • Christian Lindh
  • Bo A Jönsson
  • Anders Glynn
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Nutrition and Dietetics

Keywords

  • Breastfeeding, Diet, Fish intake, Perfluorinated compounds, PFAA
Original languageEnglish
Pages (from-to)2206-2215
JournalMolecular Nutrition and Food Research
Volume57
Issue number12
Publication statusPublished - 2013
Publication categoryResearch
Peer-reviewedYes