Shaping acoustofluidic landscapes to profile and separate cells and sub-micron particles

Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

Abstract

Acoustophoresis, where flow and acoustic fields are used to separate suspended objects, is getting increasingly more attention for cell and bacteria-handling applications relating to medicine and biology. Major benefits are flexibility in design, gentleness to cells and that relatively large forces can be exerted on suspended objects compared to competing technologies. Two important features limit acoustophoresis. First, the strong size dependency hampers separation of cells based on the underlying properties density and compressibility. Second, the presence of acoustic streaming introduces a lower size limit of objects that can be manipulated by primary radiation forces. To address these problems, we explore the action of acoustic fields on liquids of inhomogeneous acoustic properties which introduce stabilizing forces in the bulk.

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Subject classification (UKÄ) – MANDATORY

  • Medical Laboratory and Measurements Technologies
Original languageEnglish
Title of host publication2017 IEEE International Ultrasonics Symposium, IUS 2017
PublisherIEEE Computer Society
ISBN (Electronic)9781538633830
Publication statusPublished - 2017 Oct 31
Publication categoryResearch
Peer-reviewedYes
Event2017 IEEE International Ultrasonics Symposium, IUS 2017 - Washington, United States
Duration: 2017 Sep 62017 Sep 9

Conference

Conference2017 IEEE International Ultrasonics Symposium, IUS 2017
CountryUnited States
CityWashington
Period2017/09/062017/09/09