Sialylation of IgG antibodies inhibits IgG-mediated allergic reactions

Research output: Contribution to journalLetter

Abstract

In presence of high allergen dosis besides IgE also IgG antibodies can induce allergic reactions, whose severity is dependent on the induced type of IgG Fc glycosylation, what should be considered for new AIT protocols containing new adjuvants.

Details

Authors
  • Alexandra Epp
  • Juliane Hobusch
  • Yannic C Bartsch
  • Janina Petry
  • Gina-Maria Lilienthal
  • Carolien A M Koeleman
  • Simon Eschweiler
  • Christian Möbs
  • Ashley Hall
  • Suzanne C Morris
  • Dominique Braumann
  • Christine Engellenner
  • Josephine Bitterling
  • Johann Rahmöller
  • Alexei Leliavski
  • Robina Thurmann
  • Kelley W Moremen
  • Richard T Strait
  • Véronique Blanchard
  • Arnd Petersen
  • Timo Gemoll
  • Jens K Habermann
  • Frank Petersen
  • Andreas Nandy
  • Helga Kahlert
  • Michael Hertl
  • Manfred Wuhrer
  • Wolfgang Pfützner
  • Uta Jappe
  • Fred D Finkelman
  • Marc Ehlers
Organisations
External organisations
  • University of Lübeck
  • Leiden University Medical Centre
  • Philipp University of Marburg
  • University of Cincinnati College of Medicine
  • Charité Universitätsmedizin Berlin
  • Research Center Borstel
  • University of Georgia
  • Allergopharma GmbH
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Immunology in the medical area
Original languageEnglish
Pages (from-to)399-402.e8
JournalJournal of Allergy and Clinical Immunology
Volume141
Issue number1
Early online date2017 Jul 17
Publication statusPublished - 2018
Publication categoryResearch
Peer-reviewedYes