Smoking impacts endogenous estradiol and testosterone levels in young healthy women

Research output: Contribution to journalPublished meeting abstract

Abstract

Introduction: The purpose of the study was to elucidate the association between smoking and estradiol (E2) and testosterone (T) levels in young healthy women from highrisk families. Cigarette smoke contains multiple carcinogens and is considered a risk factor for breast cancer. However, tobacco also contains aromatase inhibiting substances, but the impact on hormonal levels in young women at the age when breast cancer is initiated is unclear and needs further elucidation. Material and methods Between 1996 and 2002, 258 healthy women from high-risk breast cancer families in Sweden were enrolled in a study on the impact of lifestyle factors in women

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Authors
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Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Cancer and Oncology

Keywords

  • aromatase, BRCA1 protein, carcinogen, cigarette smoke, endogenous compound, estradiol, hormone, oral contraceptive agent, testosterone, adult, anthropometry, blood, breast cancer, breast feeding, cancer family, cancer risk, drug combination, female, gene mutation, human, lifestyle, linear regression analysis, luteal phase, major clinical study, nullipara, nurse, oral contraceptive use, pill, questionnaire, risk factor, smoking, statistical significance, Sweden, waist hip ratio
Original languageEnglish
Article numberAbstract 4263
JournalCancer Research
Volume77
Issue number13 Suppl
Publication statusPublished - 2017
Publication categoryResearch
Peer-reviewedYes
EventAmerican Association for Cancer Research (AACR) 108th Annual Meeting 2017 - Washington, DC, United States
Duration: 2017 Apr 12017 Apr 5