Solubilisation of model adjuvants by Pluronic block copolymers.

Research output: Contribution to journalArticle

Abstract

The effect of two model adjuvants (benzyl benzoate and benzyl alcohol) on the structure and dynamics of three Pluronic triblock copolymers (P85, P105 and F127) was studied using small-angle neutron scattering and pulsed-field gradient NMR. The two adjuvants studied have different aqueous solubilities. It was found that both adjuvants promoted the micellisation of the Pluronic block copolymers. In addition they lead to a swelling of the micelles, as shown by small-angle neutron scattering. From the pulsed-field gradient NMR results it was possible to determine the amount of adjuvant bound to the micelles.

Details

Authors
  • Melissa Sharp
  • Clive Washington
  • Terence Cosgrove
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Natural Sciences
  • Physical Sciences
Original languageEnglish
JournalJournal of Colloid and Interface Science
Early online date2010 Jan 11
Publication statusPublished - 2010
Publication categoryResearch
Peer-reviewedYes