Splenic Metabolic Activity Predicts Risk of Future Cardiovascular Events: Demonstration of a Cardiosplenic Axis in Humans.

Research output: Contribution to journalArticle


This study sought to determine whether splenic activation after acute coronary syndrome (ACS) is linked to leukocyte proinflammatory remodeling and whether splenic activity independently predicts the risk of cardiovascular disease (CVD) events.


  • Hamed Emami
  • Parmanand Singh
  • Megan MacNabb
  • Esad Vucic
  • Zachary Lavender
  • James H F Rudd
  • Zahi A Fayad
  • Joshua Lehrer-Graiwer
  • Magnus Korsgren
  • Amparo L Figueroa
  • Jill Fredrickson
  • Barry Rubin
  • Udo Hoffmann
  • Quynh A Truong
  • James K Min
  • Amos Baruch
  • Khurram Nasir
  • Matthias Nahrendorf
  • Ahmed Tawakol
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Pharmacology and Toxicology
  • Medicinal Chemistry
Original languageEnglish
Pages (from-to)121-130
JournalJACC: Cardiovascular Imaging
Issue number2
Publication statusPublished - 2015
Publication categoryResearch